Arthrosamid®

Arthrosamid® Injections for Knee Osteoarthritis

An innovative hydrogel injection designed to relieve pain, reduce stiffness, and improve knee function in patients with knee osteoarthritis (OA). Unlike other treatments, Arthrosamid integrates with the knee’s joint lining (synovium) to provide long-term cushioning and protection.

Arthrosamid® offers a long-lasting, non-surgical solution for knee osteoarthritis, helping patients regain mobility and improve quality of life.

Currently Arthrosamid® is only available in Australia via application to Canberra (TGA). Dr Ibrahim and his team can help arrange this.

Arthrosamid Australia

How is Arthrosamid® Administered?

Before treatment with Arthrosamid®, you will have a local anaesthetic to numb the area around your knee. You should also be given antibiotics ahead of this to protect you from any potential risk of infection.

Your knee is cleaned prior to treatment. Arthrosamid® is then singularly injected into your knee’s synovial cavity. This is sometimes performed with the help of ultrasound. The needle is then removed and a bandaid is placed over the injection site.

Arthrosamid® distributes within the synovial fluid and begins to stick to and mesh with the synovial tissue.

Frequently Asked Questions

How it works
  • Arthrosamid is a non-biodegradable hydrogel made mostly of water and a cross-linked polyacrylamide backbone.
  • Once injected, it meshes with the synovial tissue, thickening the joint lining and gradually reducing pain.
  • Pain relief usually begins within 6–8 weeks and can last for several years.
  • Adults with knee OA who have not found relief from other treatments like pain medication, physiotherapy, PRP, or hyaluronic acid.
  • Not suitable for patients with joint infections, inflammatory arthritis, recent knee surgery, or certain bleeding disorders.
  • Administered under local anaesthetic, often with ultrasound guidance.
  • Patients take antibiotics beforehand to reduce infection risk.
  • Procedure takes about 30–45 minutes.
  • Most patients can walk and drive afterward, but avoid strenuous activity for 48 hours.
  • Generally safe; mild swelling, redness, or discomfort at the injection site may occur.
  • High success rate, with over 70% of patients experiencing significant pain relief and improved mobility.
  • Arthrosamid is available in Australia via a TGA application.
  • Cost is $4,800 per knee; not covered by Medicare or private health insurance.
  • Initial consultation with Dr Ameer Ibrahim is required; interstate consultations available via video.

Articles

PRP for Knee Osteoarthritis: What the Latest Research Shows

New research continues to strengthen the evidence for platelet-rich plasma (PRP) as a treatment option for knee osteoarthritis. Recent studies suggest PRP can provide meaningful improvements in pain and function, particularly for people with mild-to-moderate osteoarthritis. But does the type and concentration of PRP matter, and how long can the benefits last? We explore what the latest research shows and what it could mean for patients considering PRP for their knee.

Optimising PRP Outcomes in Knee Osteoarthritis

Optimising nutrition—particularly collagen, vitamin C, and an anti-inflammatory diet—may support healing and enhance outcomes following PRP treatment for knee osteoarthritis.

Why total platelet dose matters?

Across recent syntheses and expert reviews, higher total platelet numbers delivered to the joint are associated with better clinical outcomes, particularly for function and durability of effect.