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Evidence-based information to support informed care

This collection of articles provides clear, evidence-based information on musculoskeletal conditions, treatments, injury management and help patients better understand their condition and treatment options and to support informed conversations with their healthcare provider.

Content is informed by clinical experience and current medical research, with references included where relevant.

“Runner’s Trots”: The Real Medical Reason Endurance Athletes Sometimes Lose Bowel Control

If you're considering PRP for knee osteoarthritis, two of the biggest questions are how many injections are needed and how long the results may last. Recent research provides useful insight into both, with many clinical trials using a short course of 2–3 injections rather than a single treatment. Our latest evidence update looks at the durability of PRP, how platelet concentration may influence the length of benefit, and when a repeat course may be considered for patients who respond well.

PRP for Knee Osteoarthritis: How Many Injections Do You Need, and How Long Does Relief Last?

If you're considering PRP for knee osteoarthritis, two of the biggest questions are how many injections are needed and how long the results may last. Recent research provides useful insight into both, with many clinical trials using a short course of 2–3 injections rather than a single treatment. Our latest evidence update looks at the durability of PRP, how platelet concentration may influence the length of benefit, and when a repeat course may be considered for patients who respond well.

Rotator Cuff Tendinopathy and PRP: Modest but Durable Benefit

Rotator cuff tendinopathy and partial-thickness tears are common causes of persistent shoulder pain, particularly when symptoms don't settle with rehabilitation alone. Research into PRP is growing, with recent trials suggesting its benefits may be modest but more durable over time compared with corticosteroid injections. Our latest evidence update explores the shoulder-specific research, including partial-thickness tears, injection technique and why precise targeting and a structured strengthening program remain important when considering PRP.

Plantar Fasciopathy and PRP: How Does It Compare to Steroid Injections?

Plantar fasciopathy can cause persistent, often frustrating heel pain when conservative treatments haven't provided enough relief. While corticosteroid injections may provide faster short-term improvement, research suggests PRP may offer greater benefits as symptoms are followed over the longer term. Our latest evidence update examines the research comparing PRP and corticosteroid injections, including differences in pain relief, ultrasound findings and outcomes at six months and beyond.

Patellar Tendinopathy (Jumper’s Knee) and PRP

Patellar tendinopathy can be a stubborn and slow-to-resolve injury, particularly for athletes involved in jumping and running sports. While progressive tendon-loading exercise remains the foundation of treatment, PRP is increasingly being investigated as an option when symptoms persist. Our latest evidence update explores what injection-comparison research shows about PRP for jumper’s knee — including how leukocyte-poor PRP, high-volume injection techniques and combination treatments may influence outcomes.

How PRP Is Prepared — and Why the Preparation Method Matters

Not all PRP injections are the same. The preparation process can affect the concentration of platelets and white blood cells in the final injection — and research suggests these differences may influence treatment outcomes. Our latest evidence update explains the difference between leukocyte-rich and leukocyte-poor PRP, why the ideal formulation can vary depending on the condition being treated, and what platelet concentration may mean for the duration of benefit.

PRP vs Hyaluronic Acid for Knee Osteoarthritis: What Head-to-Head Trials Show

How does PRP compare with hyaluronic acid for knee osteoarthritis? Head-to-head clinical trials are increasingly showing that PRP can provide greater improvements in pain and symptoms over the longer term, with benefits particularly evident at 12 months. Our latest evidence update looks at what randomised trials and meta-analyses actually show when PRP and HA are compared directly — and what these findings could mean when considering your treatment options.

PRP for Knee Osteoarthritis: What the Latest Research Shows

New research continues to strengthen the evidence for platelet-rich plasma (PRP) as a treatment option for knee osteoarthritis. Recent studies suggest PRP can provide meaningful improvements in pain and function, particularly for people with mild-to-moderate osteoarthritis. But does the type and concentration of PRP matter, and how long can the benefits last? We explore what the latest research shows and what it could mean for patients considering PRP for their knee.

Optimising PRP Outcomes in Knee Osteoarthritis

Optimising nutrition—particularly collagen, vitamin C, and an anti-inflammatory diet—may support healing and enhance outcomes following PRP treatment for knee osteoarthritis.

Why total platelet dose matters?

Across recent syntheses and expert reviews, higher total platelet numbers delivered to the joint are associated with better clinical outcomes, particularly for function and durability of effect.

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